THE COMPLETE SKIN SECRETOME DISCOVERY
A breakthrough born from scientific curiosity.
During groundbreaking cancer research, world-renowned stem-cell scientist Dr. Hans Keirstead made an unexpected discovery: the complete skin secretome— hundreds of growth factors and exosomes, plus fetuin-A, the missing link no other formulation had captured. It became the foundation of LevEllis’ mission and its first expression, PROVOQUE™ Facial Serum.
THE SCIENTIST
A discovery bigger than skin
Dr. Hans Keirstead, PhD
For more than three decades, Dr. Hans Keirstead has been at the forefront of regenerative medicine. An internationally recognized stem cell scientist and CEO of AIVITA Biomedical, his research has focused on unlocking the body's natural ability to regenerate.
His pioneering work led to the discovery of the complete skin-specific secretome—the scientific foundation behind PROVOQUE and a new approach to supporting healthy skin through coordinated biological signaling.
THE SURGEON
Proof, four years in the making
Laura Ellis, MD
For more than two decades, Dr. Ellis has been at the forefront of aesthetic medicine. A board-certified surgeon, molecular biologist, and entrepreneur, her career has focused on translating scientific innovation into meaningful patient outcomes.
After more than three years of clinical evaluation in her own practice, Dr. Ellis recognized the potential of the complete skin-specific secretome. She founded LevEllis and secured the exclusive worldwide license to bring this breakthrough technology to market through PROVOQUE.
Unlocking new possibilities in regenerative aesthetics
THE PROVOQUE STANDARD
Complete Tissue-Specific Cell Signaling
01 Complete
The full secretome, not fragments.
02 Tissue-Specific
Sourced from skin progenitor cells.
03 Peak Vitality
Undegraded by age.
WHY SOURCE MATTERS
Skin remembers where it came from.
Cells carry tissue memory. The source of a cell shapes the signals it produces. Biology derived from scar, fat, or bone marrow cannot fully replicate the natural signaling language of healthy skin.
OUR MISSION
Advancing regenerative science through breakthrough discovery.
Inspired by Dr. Keirstead's discovery of the skin-specific, fetuin-A-powered secretome, our mission is to remain dedicated to setting a new standard in topical aesthetics by continuously pursuing breakthrough discoveries that challenge conventional approaches and awaken skin's full regenerative power.
OUR PRINCIPLES
The principles that guide every breakthrough.
Provocative innovation
We are committed to advancing the science of aesthetic medicine through rigorous research and cutting-edge technologies.
Clinical precision
Placing patient well-being and satisfaction at the core of every decision—from product development to post-treatment.
Scientific authority